Creutzfeldt-Jakob Disease

Sporadic: about 85% of case. [4] It is rare at around one case per million population per year. It is found throughout the world, and is thought to be due to a spontaneous mutation of the prion protein. It is not transmitted. Hereditary: a little under 15% of cases. This variant occurs in family clusters with a dominant pattern of inheritance. [4] Iatrogenic CJD: may be transmitted by instruments used in neurosurgery, tissue grafts, and hormones derived from cadaveric pituitary glands. [5]Other healthcare workers have also been affected. [6] nvCJD: is linked with BSE discovered in cattle in 1986 and is believed to be transmitted through eating infected meat products, especially through parts of the central nervous system (CNS). It was first recognised in 1996 and no cases had been identified with infection before 1994.